The popliteal artery, through numerous smaller branches, supplies blood to the knee joint and muscles in the thigh and calf. It is accompanied, along its length, by the popliteal vein.
Embryologically, the popliteal artery is derived from the fetal sciatic artery, which is distinct from the femoral artery.
Its pulse can be palpated behind the knee, but is generally more challenging to find than other arteries of the leg.