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Precocious puberty

Precocious puberty
ICD-10 E30.1
ICD-9 259.1
ICD-O:
OMIM
DiseasesDB
MedlinePlus
eMedicine

Precocious puberty means early puberty.

Contents

Types and causes

Early pubic hair, breast, or genital development may result from normal but early maturation or from several abnormal conditions. Early puberty which is normal in every way except age is termed idiopathic central precocious puberty. It may be partial or transient. Central puberty can also occur prematurely if the inhibitory system of the brain is damaged, or a hypothalamic hematoma produces pulsatile gonadotropin-releasing hormone (GnRH). Secondary sexual development induced by sex steroids from other abnormal sources (gonadal or adrenal tumors, congenital adrenal hyperplasia, etc.) is referred to as peripheral precocious puberty or precocious pseudopuberty.

Clinical significance

Early sexual development deserves evaluation because it may :

  1. induce early bone maturation and reduce eventual adult height,
  2. cause significant social problems, or
  3. indicate the presence of a tumor or other serious problem.

Measures

No single age limit reliably separates normal from abnormal processes, but the following age thresholds for evaluation will minimize the risk of missing a significant problem:

  • Pubic hair or genital enlargement in boys with onset before 9 years.
  • Breast development in boys before appearance of pubic hair and testicular enlargement.
  • Pubic hair before 8 or breast development in girls with onset before 7 years.
  • Vaginal bleeding in girls before 10 years.

Suggested causes: Environmental estrogens, sedentary lifestyle, and obesity

Other notes

Medical evaluation is sometimes necessary to recognize the few children with serious conditions from the majority who have entered puberty early but are still medically normal.

Children (esp. girls) who are obese are more likely to physically mature earlier.

Precocious puberty can make a child able to conceive when very young. Both sexes have become parents before age 10. The youngest mother on record is Lina Medina, who gave birth at the age of 5 years, 7 months and 21 days.

See also

References

  • Traggiai C, Stanhope R (2003). "Disorders of pubertal development". Best Pract Res Clin Obstet Gynaecol 17 (1): 41-56. PMID 12758225.

External links


The content of this page is retrieved from http://en.wikipedia.org/wiki/Precocious_puberty under GFDL